She hopes that the new CTF enterprise will not only benefit patients with NF, but may be of value to the larger rare disease community. Op-eds by Pande defining trends and issues in this emerging space have been published by The New York Times, Scientific American, and Forbes, among others. His responsibilities include management of multiple business units and commercial operation. His research laboratory focused on understanding the inherited basis for blood lipids and myocardial infarction and using these insights to improve preventive cardiac care. He has authored or co-authored more than 350 scientific and clinical publications and is the senior editor of Brocklehurst’s Textbook of Geriatric Medicine and Gerontology currently in its 8th edition. Amir also earned both his MS and BS in Materials Science and Mechanical Engineering at the University of California, Berkeley. Learn how University of Maryland, using Digital Twins, solves the real problem of how to give students the individual experience and training they need when it isn’t possible to go into a physical lab. The venture team has invested in ~100 companies and ~20 funds pursuing products, technologies and services, relevant to all aspects of Pfizer’s business, since inception in 2004. Imago acquired Elan Pharmaceuticals’ preclinical assets, including JNK, from which all assets were developed and partnered or sold to biotech or pharmaceuticals to continue their development. In his time at the BIA Steve has developed new member groups focused on cell and gene therapy, genomics and engineered biology. Mr. Nelsen holds an M.B.A. from the University of Chicago and a B.S. Irene worked at Elan Pharmaceuticals, contributed to Alzheimer’s disease, Parkinson’s disease and Multiple Sclerosis Programs. investors. Prior to AstraZeneca, José served as the Physician-in-Chief at Memorial Sloan Kettering Cancer Center (MSK) and Professor of Medicine at Weill Cornell Medical College from 2012 to 2018. Robert Califf, Head of Clinical Policy and Strategy for Verily and Google Health and antibiotics innovation, value based healthcare, precision medicine Yvonne serves on the board of directors of Pacira Pharmaceuticals, American Funds, the Scientific Advisory Committee of the Bill and Melinda Gates Foundation and is a member of the Discovery Council of Harvard Medical School. Session Leader: Steve Yang, Co-CEO, WuXi AppTec, 8:40 Better Medicines Faster Dr. Jaffray holds multiple patents and has authored more than 275 peer-reviewed publications in topics related to cancer, including, the development of new radiation treatment machines, exploring the fundamental limits of imaging system performance, and the development of novel nanoparticle formulations for improved detection of cancer. At weekends Kate spends time in Wales where she rides horses and mountain bikes, grows vegetables and competes in bog snorkelling competitions. As the founding investor of a16z’s Bio Fund, Pande leads the firm’s investments at the cross section of biology and computer science, including applications in computation, machine learning, and artificial intelligence in healthcare; digital therapeutics; diagnostics; and other novel transformative scientific advances applied to industry that take bio beyond healthcare. Chris Chen, CEO, WuXi Biologics Bahija was named the 2017 Woman of the Year by the Healthcare Businesswomen’s Association. to health promotion and disease prevention enabled by a transformed skis and loves to travel the world. IPN007 was purchased by Biogen for up to $1.4 billion and is testing in Phase 2 studies for PSP and AD. He She is a Council Member of the Government-University-Industry Research Roundtable of the National Academies of Sciences, Engineering and Medicine. As past President of the American Association of Cancer Research (AACR), José worked collaboratively with the AACR Board of Directors and the AACR membership to further the mission to cure cancer through research. Prior to Takeda, Dr. Hitchcock had served in senior leadership positions in the research organizations at Eli Lilly and Amgen. She has managed departments and groups working on a variety of projects for the discovery and development of novel therapeutics for neurological disorders. This partnership has now delivered approval of Enhertu in HER2-positive metastatic breast cancer (as well as new data on 4 sub-types gastric cancer, non-small cell lung cancer, colorectal cancer and breast cancer) and most recently with the addition of DS-1062, a high-potential second-generation antibody drug conjugate against TROP-2, secured the potential to redefine standards of care across a range of cancers. Today, the term ‘digital twin’ is being used with increasing frequency, but with little consistency across multiple industries. He was the founding Finally he believes in a population based approach She is an editorial advisor to Xconomy, a US news company. Dr. Varney holds a B.S. When it comes to context, by 2050, the world’s population is Session Leader: Selina Koch, Executive Editor, BioCentury, 9:20 The Path to Acceleration shubs-subdomains.txt - Free ebook download as Text File (.txt), PDF File (.pdf) or read book online for free. With an already diverse portfolio of five existing oncology medicines, and an industry-leading pipeline, José’s vision for transforming survival in cancer is based on treating earlier; delivering deeper responses; better monitoring for relapse; using AI and big data to map cancer inter-dependencies; and breaking the traditional treatment paradigms that currently restrict opportunity for patients. McMurry-Heath received her MD/PhD from Duke University’s Medical Scientist Training Program, becoming the first African American ever to graduate from the prestigious dual-degree program. in human biology from Stanford University. Prior to InterWest health start-ups that serve high unmet needs. Karen Chen is the Chief Executive Officer of the Spinal Muscular Atrophy Foundation, responsible for overseeing the full range of scientific and drug discovery programs, as well as managing the operations activities. Dr. David Chang obtained his Bachelor’s degree in Chemical Engineering from National Taiwan University in Taiwan, and the Master’s and PhD degrees in Biochemcial Engineering from MIT in Massachusetts, USA. Digital Twin lifecycle can mean different things to different stakeholders. Bahija has authored more than 70 peer-reviewed publications and has more than 15 patents. This keynote address will explore the possibilities being created by the digital twin economy. Regev is a leader in deciphering molecular circuits that govern cells, tissues and organs in health and their malfunction in disease. Importantly, the system becomes more robust over time with the addition of new data. In recent years, BIM has emerged as the gold standard for 3-D digital modeling and continues to be the way architects, developers, construction managers, owners and contractors coordinate complex construction projects. She is a co-author and co-inventor to over 40 scientific publications and issued or pending patents. A conversation between Robert Nelsen, Co-Founder and Managing Director of ARCH Venture Partners and Michael Martin, Global Head of Takeda Ventures, 8:00 Welcome In addition, she chairs the Healthcare Advisory Board of the Partnership Fund for NYC. A SaaS based solution allowing for real-time processing of nearly 1TB/s with over 84% Open Data from sources including ESA, NASA, and IoT providers. Dr. Michael Rosenblatt’s career has been in academia, pharma and biotech/venture. in history from the University of Pennsylvania and received his M.D. Prior to joining Polaris, Amir completed his ScD as a Hertz Fellow in Chemical Engineering at the Massachusetts Institute of Technology with a minor in Biology under the guidance of Dr. Robert Langer. global health architecture based on purposeful public and private He graduated summa cum laude with a B.A. She is also the immediate past president of the Association of Women in Science. Dr. Hui Cai joined WuXi AppTec in 2009 as Vice President of Business Development, and is currently Vice President of Corporate Alliances, and Head of PR and Corporate Communications. She has overall responsibility for Pfizer Ventures and directly manages investments in all funds and specifically the portfolio companies: Artios, Cydan, Imara, Ixchelsis, Levicept, Ravenna, Simcha, System 1. She negotiated agreements with major biopharma, life sciences, food and cosmetics companies to advance the translation of discoveries into products and create a revenue-generating product pipeline and worked with scientific founders and investors to create new startup companies. Previously, Dr. Yang served as Vice President and Head of Asia R&D at Pfizer based in Shanghai, and as Executive Director and head of Pfizer’s global R&D strategic management group based in the United States. Kate Bingham, Managing Partner, SV Health Investors Over a career spanning 23 years in the pharmaceutical and biotechnology arena, Dr. Hitchcock has been fortunate to work with teams that have developed therapeutic drug candidates spanning a variety of disease indications. Dr. Cai is a Councilor of the American Chemical Society (ACS), a member of BayHelix, and a member of the UCSD Alumni Board. Dr. Chen obtained bachelor’s degrees in chemical engineering and automation from Tsinghua University and his Ph.D. in chemical engineering from the University of Delaware. He was President of Beth Israel Deaconess Medical Center and Director of the Harvard-MIT Division of Health Sciences and Technology. understanding the basic processes that control T-cell activation and immune tolerance in autoimmunity, Dr. Chen is the co-author and co-inventor of over 70 publications and patents. Her lab has pioneered foundational experimental and computational methods in single-cell genomics, working toward greater understanding of the function of cells and tissues in health and disease, including autoimmune disease, inflammation and cancer. Dr. Steve Hitchcock is Head of Research for Takeda Pharmaceutical Company, Ltd. He is also WuXi AppTec’ s Head of Research Service Division and Head of WuXi Testing. What to Expect Next? Annette, a PhD in Biochemistry, has leadership experience in both the academic and pharma/biotech research enterprise in Italy, Belgium, France, and the USA. Dr. Chen has served on the National Institute of Neurological Disorders and Stroke (NINDS) National Advisory Council. Michael Rosenblatt, CMO, Flagship Pioneering She also is the Chief Executive Officer and Cofounder of Imago Pharmaceuticals and on the Board of Directors of Nitrome Biosciences. Dr. Bluestone is the President and CEO of Sonoma Biotherapeutics and the A.W. This was always the case with mechanical and electronic locks and now internet connected door locks present new challenges and introduce cyber-physical risks. In 2005, Dr. Varney was recruited to Genentech, the US based R&D organization of Roche, to expand the organization’s drug discovery capabilities to include small molecules. He joined ARCH at its founding and played a significant role in the early sourcing, financing and development of more than 100 companies, including twenty-three which have reached valuations exceeding $1 billion. In 1997, the Agouron team launched Viracept, an HIV protease inhibitor that achieved the highest first year launch sales of any biotech product at the time. Digital twins are moving into the mainstream of business and government. Dr. Chen is a senior research scientist and manager with over 30 years of experience, including 15 years in the pharmaceutical industry, planning, directing, and conducting preclinical research. Amir also serves on the Partners Innovation Fund and the Investment Advisory Committee for The Engine at MIT, and helped launch the MIT Sandbox Innovation Fund as its active president. He was made OBE for services to innovation in 2017. 811 Likes, 2 Comments - UW-Milwaukee (@uwmilwaukee) on Instagram: “Happy #PantherPrideFriday Tag us in your photos to be featured on our page or in our Photos of…” Dr. Soll’s contributions led to the discovery of the HCV NS5A inhibitor elbasvir (a component of Zepatier®) in the Merck-WuXi partnership, the JAK2 inhibitor fedratinib at TargeGen which formed the basis of the $7B partnership between Celgene and Impact Biomedicines, and more than 10 other clinical stage drugs throughout his career. src/public/js/zxcvbn.js This package implements a content management system with security features by default. Louis has served on the Board of Deputies since 1956 and is an executive member of Manchester Council for Community Relations. He is also developing therapies for treating and preventing AD using human brain organoid models of the disease. Healthcare, then as the Global Head for Health and Healthcare Learn how, with customers spread all over the world and ship cranes used mainly at remote locations, they train operators in the handling of commodities like coal, iron ore and grain in trans-shipment operations, thereby increasing customer productivity and lowering equipment down-time due to training. She received her BA from Colorado University in Molecular, Cellular and Developmental Biology and Ph. Bruce Thompson, Executive Director Spatial Services | Department of Customer Service NSW Government. In 2020, she was the recipient of several accolades including the Lurie Prize in Biomedical Sciences, Massachusetts General Hospital’s Jonathan Kraft Prize, and the European Society of Human Genetics’ Mendel Award. He served as Deputy Commissioner for Medical Products and Tobacco in the U.S. Food and Drug Administration (FDA) from 2015-2016, and as Commissioner of Food and Drugs from 2016-2017. She also serves on the board of WellTok and previously served on the boards of Labrys (acquired A medical doctor and molecular immunologist by training, Dr. McMurry-Heath becomes just the third leader of the world’s largest biotechnology advocacy group since BIO’s founding in 1993. His professional background includes venture capital, pharma business development and broad R&D experiences with an integral role in the discovery and development of 17 innovative investigational drugs and 4 commercial products. Thank you for tuning into our programs, and a special thank you to our WuXi Global Forum 2021 partners: BioCentury, BioIndustry Association, BioWorld, Biocom, California Life Sciences Association, Children’s Tumor Foundation, Endpoints News, MBC BioLabs, Pharma Intelligence | informa, QB3 and Swiss Biotech Association. OnePlus is gearing up to announce the OnePlus 9 and 9 Pro models later this month. He has served as a consultant to pharmaceutical, biotechnology and health care companies. During Dr. Chen’s tenure, WuXi Biologics has assembled one of the world’s largest biologics teams, with over 6,000 employees enabling 80 Investigational New Drug (IND) programs and 7 Biologics License Application (BLA) programs per year. He is also the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. She has 20 years of experience funding, growing and Ameet was most recently an Executive Committee member at Sanofi SA, where he served as Chief Medical Officer, Head of Medical, and Chief Digital Officer and was responsible for enhancing Sanofi’s strategy to integrate digital technologies and medical science to ultimately improve patient outcomes. A property management portfolio is made up of physical buildings. Prior to WuXi, Dr. Cai spent 10 years at Johnson & Johnson Pharmaceutical Research and Development leading multiple drug discovery programs in the therapeutic areas of inflammation and autoimmune diseases. Liebherr is not only one of the world's largest manufacturer of construction machinery, they also help to shape technological advances across many other industries. She has also served as the founding chief executive officer of a number of PureTech’s Founded Entities. Richard Soll, Head of WuXi AppTec’s Boston Office; Senior Advisor of Strategic Initiatives, 8:05 Shaping the Next Twenty Years The full event agenda and distinguished speaker bios can be found below. Prior to joining Verve, he served as director of the Massachusetts General Hospital (MGH) Center for Genomic Medicine and was the Ofer and Shelly Nemirovsky MGH Research Scholar. This he has done first as a senior an environment in which people live healthier and longer lives with Dr. Rudolph Tanzi is the Director of the Genetics and Aging Research Unit, Co-Director of the McCance Center for Brain Health, Co-Director of the MassGeneral Insititute for Neurodegenerative Disease, and Vice-Chair of Neurology (Research), at Massachusetts General Hospital. Howard Fillit, Founding Executive Director and CSO, Alzheimer’s Drug Discovery Foundation In this role she leads the Innovation Center team to build, advance, and manage the External R&D portfolio of co-investments spanning across pharmaceutical, consumer health and medical devices. and Canaan, Nina worked at Bay City Capital, Oracle Partners and the Kaiser Family Foundation. capital intensive, hospital centric, interventions driven systems are Current Canaan investments include Pact Pharma, Tizona, Tyra and Vijay Pande, General Partner, Andreessen Horowitz With over 225 specifications to its name OMG has continued to develop technologies through membership communities. health security across borders, and with access to affordable care. Therapeutics. WuXi AppTec provides a broad portfolio of R&D and manufacturing services that enable companies in the pharmaceutical, biotech and medical device industries worldwide to advance discoveries and deliver groundbreaking treatments to patients. She was previously a Cofounder and the CSO of Imago Pharmaceuticals. Dr. Shawver is the Founder of The Clearity Foundation, a nonprofit organization helping women with ovarian cancer to improve their treatment options and currently serves on the board of Relay, Nkarta, and Cleave Therapeutics. On such matters and many others, he also RD Mel Gomez, Alexander Mattingly, Michael Connelly @ University of Maryland. Under his leadership, gRED teams discovered and developed successful medicines that include Venclexta with AbbVie, the first bcl-2 inhibitor and Polivy, an antibody drug conjugate for the treatment of DLBCL. She was also Executive Vice President of AstraZeneca and a member of its senior executive team. Dr. Varney also focused on building a team-based culture empowered to clear the path to patients. Steve is the visible face of the vibrant UK life sciences industry to government and media. Regev has served on multiple corporate advisory, scientific advisory, and journal editorial boards, including the advisory committee to the National Human Genome Research Institute at the National Institutes of Health. Amir currently represents Polaris as a Director of AgBiome, CAMP4 Therapeutics, Dewpoint Therapeutics, Freenome, Metacrine Therapeutics, Morphic Therapeutic (NASDAQ: MORF), Scholar Rock (NASDAQ: SRRK), and Syros Pharmaceuticals (NASDAQ: SYRS). Session Leader: Edward Hu, Vice Chairman of the Board and Global Chief Investment Officer, WuXi AppTec, 8:00 Welcome As part of this the Twin has been deployed within Mott Macdonald's Leeds office to understand social distancing within the building and the implications of office layouts and the relationship to the city's Covid public transport planning. He led UHN’s information technology transformation, designed the roadmap for digital transformation. From November 2017 – February 2020, Dr. Shawver was President, Chief Executive Officer and Director of Synthorx, Inc, acquired by Sanofi in January 2020 for $2.5B. Dr. Baselga’s long standing research interests are in the development of targeted agents for the treatment of breast cancer and in studying strategies to overcome mechanisms of resistance, with over 500 peer-reviewed publications to date. He has forged links for the sector across the USA, Europe and in China. Prior to joining Sanofi, Ameet was the Global Head of Medical Affairs and a member of the Pharma Executive Committee at Novartis Pharma AG, where he led the establishment of a Real World Evidence Center of Excellence and Digital Medicine capabilities. Across his career in R&D, Ameet has been responsible for the development of over 20 drugs, four of which went on to become blockbusters Karen Chen, CEO, Spinal Muscular Atrophy Foundation He has been awarded the DeLano Prize in Computation; a Guinness World Record for Folding@Home; the American Chemical Society Thomas Kuhn Paradigm Shift Award; and was selected for MIT TR10.
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